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Don’t Mix and Match: What HVAC Pros Should Know About R-454B Shortages and R-32 Solutions

July 3, 2025

As the HVAC industry moves toward lower-GWP refrigerants, contractors nationwide face a growing challenge: R-454B, the most common A2L replacement for R-410A in many new systems, is increasingly complex to source, and prices reflect that scarcity. The result? Installation delays, frustrated customers, and mounting pressure on technicians to find a workaround.

Sometimes, that pressure leads to risky decisions, like topping off with the wrong refrigerant or attempting to mix a substitute blend in the field. But when it comes to A2Ls, there’s no margin for improvisation. R-454B is a precise, patented blend that can’t be replaced or recreated without compromising safety, performance, or compliance.

R-32: A Safe, Proven Alternative

An increasing number of manufacturers are turning to R-32, and for good reason. With strong performance characteristics, lower GWP than R-410A, and widespread global use, R-32 offers a compelling alternative that is already gaining traction across both ducted and ductless systems.

One major benefit? Simplicity. Unlike R-454B—a 68.9%/31.1% blend of R-32 and R-1234yf—R-32 is a single-component refrigerant. When servicing a unit with R-454B, there’s no way to know how much of each component is lost during a leak, meaning the entire system must be evacuated before recharging. That extra labor and refrigerant loss add up fast. With R-32 systems, that costly guesswork disappears.

Several leading HVAC brands have already committed to R-32 for their next-generation equipment. For contractors, this opens the door to a more flexible path forward—one where they can avoid costly delays and keep projects on track without cutting corners.

At Lessen, we recognize how critical refrigerant availability is to staying efficient and compliant. R-32 is available through Lessen Marketplace™, giving contractors access to the refrigerant and necessary equipment without the runaround.

Why Substitutions Are Still a Risk

It’s important to note that while R-32 is a viable option, it’s only safe and legal when used in systems specifically designed for it. Substituting refrigerants between systems (like charging an R-454B system with R-32 or vice versa) can cause serious issues:

  • System malfunction or failure
  • Voided warranties
  • EPA and UL standard violations
  • Unpredictable performance, especially in heating seasons

Refrigerants are engineered for exact performance within their designated systems. Mixing or substituting—even with good intentions—undermines system safety and reliability.

How Contractors Can Stay Ahead

Here are a few ways to stay proactive during the ongoing R-454B shortage:

  • Lean into R-32 Systems: Consider incorporating R-32-ready equipment into your product lineup. It’s already in wide use globally and supported by major U.S. manufacturers. Most of all, priced competitively within Lessen Marketplace.
  • Secure Your Supply Chain: Leverage larger cylinder sizes and check availability across multiple suppliers. Lessen Marketplace is one channel where R-32 can be sourced without hassle.
  • Stay Compliant: Only charge systems with their designated refrigerant. Don’t risk fines, callbacks, or compromised safety by attempting field blends or substitutions.
  • Keep Your Team Trained: With multiple A2Ls in play, proper technician training on charging procedures, leak detection, and refrigerant-specific handling is more important than ever.

Looking Forward

Hopefully, the R-454B supply situation will improve in the coming months. But with high demand and uncertain timelines, the best approach is one rooted in flexibility, safety, and preparation.

By embracing R-32 where appropriate and leveraging trusted procurement platforms like Lessen Marketplace, HVAC professionals can keep jobs moving, protect their reputation, and stay ahead of the curve as the industry evolves.

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